Predictive Metabolic Engineering: A Goal for Systems Biology
نویسندگان
چکیده
منابع مشابه
Predictive metabolic engineering: a goal for systems biology.
The landmark sequencing of Escherichia coli, Brewer’s yeast (Saccharomyces cerevisiae), Arabidopsis, and human genomes has facilitated the emergence of systems biology—a science that is currently gaining the attention of molecular biologists. In addition to satisfying our intellectual desire to have a more detailed understanding of plant biology, we need to understand how plants work well enoug...
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Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived from insight into: (i) system structure and the mechanism of biological networks such as gene regulation, protein interactions, signaling, and...
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The pursuit of science is based on empiricism enabled by advancing technologies. Theories then emerge that unify our understanding of natural order. The trinity of experimentation, theory, and technology that underlies the scientific method cannot be placed into a hierarchy of importance. Theoretical fields quickly lose substance in the absence of robust experimentation, and theoretical conundr...
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Industrial biotechnology is a rapidly growing field. With the increasing shift towards a bio-based economy, there is rising demand for developing efficient cell factories that can produce fuels, chemicals, pharmaceuticals, materials, nutraceuticals, and even food ingredients. The yeast Saccharomyces cerevisiae is extremely well suited for this objective. As one of the most intensely studied euk...
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ژورنال
عنوان ژورنال: Plant Physiology
سال: 2003
ISSN: 1532-2548,0032-0889
DOI: 10.1104/pp.103.022004